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Migration promotes mutator alleles in subdivided populations

Mutator alleles that elevate the genomic mutation rate may invade nonrecombining populations by hitchhiking with beneficial mutations. Mutators have been repeatedly observed to take over adapting laboratory populations and have been found at high frequencies in both microbial pathogen and cancer pop...

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Detalhes bibliográficos
Publicado no:Evolution
Main Authors: Raynes, Yevgeniy, Sniegowski, Paul D., Weinreich, Daniel M.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6680344/
https://ncbi.nlm.nih.gov/pubmed/30632605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/evo.13681
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