Spatial Network Mapping of Pulmonary Multidrug-Resistant Tuberculosis Cavities Using RNA Sequencing

Rationale: There is poor understanding about protective immunity and the pathogenesis of cavitation in patients with tuberculosis. Objectives: To map pathophysiological pathways at anatomically distinct positions within the human tuberculosis cavity. Methods: Biopsies were obtained from eight predet...

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Detalhes bibliográficos
Publicado no:Am J Respir Crit Care Med
Main Authors: Dheda, Keertan, Lenders, Laura, Srivastava, Shashikant, Magombedze, Gesham, Wainwright, Helen, Raj, Prithvi, Bush, Stephen J., Pollara, Gabriele, Steyn, Rachelle, Davids, Malika, Pooran, Anil, Pennel, Timothy, Linegar, Anthony, McNerney, Ruth, Moodley, Loven, Pasipanodya, Jotam G., Turner, Carolin T., Noursadeghi, Mahdad, Warren, Robin M., Wakeland, Edward, Gumbo, Tawanda
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2019
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6680310/
https://ncbi.nlm.nih.gov/pubmed/30694692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.201807-1361OC
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