Systems medicine in colorectal cancer: from a mathematical model toward a new type of clinical trial

Current colorectal cancer (CRC) treatment guidelines are primarily based on clinical features, such as cancer stage and grade. However, outcomes may be improved using molecular treatment guidelines. Potentially useful biomarkers include driver mutations and somatically inherited alterations, signali...

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Bibliografiske detaljer
Udgivet i:Wiley Interdiscip Rev Syst Biol Med
Main Authors: Castagnino, Nicoletta, Maffei, Massimo, Tortolina, Lorenzo, Zoppoli, Gabriele, Piras, Daniela, Nencioni, Alessio, Moran, Eva, Ballestrero, Alberto, Patrone, Franco, Parodi, Silvio
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley & Sons, Inc. 2016
Fag:
Advanced Reviews
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6680205/
https://ncbi.nlm.nih.gov/pubmed/27240214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/wsbm.1342
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