Increased alternative splicing of the KLF6 tumor suppressor gene correlates with prognosis and tumor grade in patients with pancreatic cancer

The aim of this study was to correlate the status of the KLF6 tumor suppressor gene including loss of heterozygozity (LOH), mutation and alternative splicing in human pancreatic cancer with tumor grade and survival. Whereas neither KLF6 loss nor mutation was identified, expression of the KLF6 altern...

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Vydáno v:Eur J Cancer
Hlavní autoři: Hartel, Mark, Narla, Goutham, Wente, Moritz N., Giese, Nathalia A., Martignoni, Marc E., Martignetti, John A., Friess, Helmut, Friedman, Scott L.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6679930/
https://ncbi.nlm.nih.gov/pubmed/18691883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejca.2008.06.030
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