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A new crystal form of human acetylcholinesterase for exploratory room-temperature crystallography studies

Structure-guided design of novel pharmacologically active molecules relies at least in part on functionally relevant accuracy of macromolecular structures for template based drug design. Currently, about 95% of all macromolecular X-ray structures available in the PDB (Protein Data Bank) were obtaine...

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Detalhes bibliográficos
Publicado no:Chem Biol Interact
Main Authors: Gerlits, Oksana, Ho, Kwok-Yiu, Cheng, Xiaolin, Blumenthal, Donald, Taylor, Palmer, Kovalevsky, Andrey, Radić, Zoran
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6679772/
https://ncbi.nlm.nih.gov/pubmed/31176713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cbi.2019.06.011
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