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Aerosolized recombinant human butyrylcholinesterase delivered by a nebulizer provides long term protection against inhaled paraoxon in macaques

The recent intentional use of nerve agents and pesticides in Europe and Afghanistan highlights the need for an effective countermeasure against organophosphates (OP) toxins. The most developed pretreatment candidate to date is plasma (native) human butyrylcholinesterase (HuBChE), which is limited in...

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Detalhes bibliográficos
Publicado no:Chem Biol Interact
Main Authors: Rosenberg, Yvonne, Fink, James, MacLoughlin, Ronan, Ooms-Konecny, Tara, Sullivan, Dennis, Gerk, William, Mao, Lingjun, Jiang, Xiaoming, Lees, Jonathan, Urban, Lori, Rajendran, Narayanan
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6679726/
https://ncbi.nlm.nih.gov/pubmed/31201777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cbi.2019.06.025
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