Aerosolized recombinant human butyrylcholinesterase delivered by a nebulizer provides long term protection against inhaled paraoxon in macaques

The recent intentional use of nerve agents and pesticides in Europe and Afghanistan highlights the need for an effective countermeasure against organophosphates (OP) toxins. The most developed pretreatment candidate to date is plasma (native) human butyrylcholinesterase (HuBChE), which is limited in...

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Библиографические подробности
Опубликовано в: :Chem Biol Interact
Главные авторы: Rosenberg, Yvonne, Fink, James, MacLoughlin, Ronan, Ooms-Konecny, Tara, Sullivan, Dennis, Gerk, William, Mao, Lingjun, Jiang, Xiaoming, Lees, Jonathan, Urban, Lori, Rajendran, Narayanan
Формат: Artigo
Язык:Inglês
Опубликовано: 2019
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6679726/
https://ncbi.nlm.nih.gov/pubmed/31201777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cbi.2019.06.025
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