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Pulmonary delivery of an aerosolized recombinant human butyrylcholinesterase pretreatment protects against aerosolized paraoxon in macaques

Butyrylcholinesterase (BChE) is the leading pretreatment candidate against exposure to organophosphates (OPs), which pose an ever increasing public and military health. Since respiratory failure is the primary cause of death following acute OP poisoning, an inhaled BChE therapeutic could prove highl...

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Detalhes bibliográficos
Main Authors: Rosenberg, Yvonne J., Laube, Beth, Mao, Lingjun, Jiang, Xiaoming, Abanto, Segundo Hernandez, Lee, Keunmyoung D., Adams, Robert
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3594399/
https://ncbi.nlm.nih.gov/pubmed/23178380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cbi.2012.11.004
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