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Minimal effects of spargel (PGC-1) overexpression in a Drosophila mitochondrial disease model

PGC-1α and its homologues have been proposed to act as master regulators of mitochondrial biogenesis in animals. Most relevant studies have been conducted in mammals, where interpretation is complicated by the fact that there are three partially redundant members of the gene family. In Drosophila, o...

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Bibliografiske detaljer
Udgivet i:Biol Open
Main Authors: George, Jack, Jacobs, Howard T.
Format: Artigo
Sprog:Inglês
Udgivet: The Company of Biologists Ltd 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6679408/
https://ncbi.nlm.nih.gov/pubmed/31292108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/bio.042135
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