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The Drosophila PGC-1 homologue Spargel coordinates mitochondrial activity to insulin signalling
Mitochondrial mass and activity must be adapted to tissue function, cellular growth and nutrient availability. In mammals, the related transcriptional coactivators PGC-1α, PGC-1β and PRC regulate multiple metabolic functions, including mitochondrial biogenesis. However, we know relatively little abo...
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| Главные авторы: | , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Nature Publishing Group
2010
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2808377/ https://ncbi.nlm.nih.gov/pubmed/19910925 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2009.330 |
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