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Minimal effects of spargel (PGC-1) overexpression in a Drosophila mitochondrial disease model

PGC-1α and its homologues have been proposed to act as master regulators of mitochondrial biogenesis in animals. Most relevant studies have been conducted in mammals, where interpretation is complicated by the fact that there are three partially redundant members of the gene family. In Drosophila, o...

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Bibliografske podrobnosti
izdano v:Biol Open
Main Authors: George, Jack, Jacobs, Howard T.
Format: Artigo
Jezik:Inglês
Izdano: The Company of Biologists Ltd 2019
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6679408/
https://ncbi.nlm.nih.gov/pubmed/31292108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/bio.042135
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