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Impact of Q141K on the Transport of Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors by ABCG2

The ATP-binding cassette transporter ABCG2 is expressed in various organs, such as the small intestine, liver, and kidney, and influences the pharmacokinetics of drugs that are its substrates. ABCG2 is also expressed by cancer cells and mediates resistance to anticancer agents by promoting the efflu...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Cells
Egile Nagusiak: Inoue, Yutaka, Morita, Takashi, Onozuka, Mari, Saito, Ken-ichi, Sano, Kazumi, Hanada, Kazuhiko, Kondo, Masami, Nakamura, Yoichi, Kishino, Tohru, Nakagawa, Hiroshi, Ikegami, Yoji
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: MDPI 2019
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6678652/
https://ncbi.nlm.nih.gov/pubmed/31340525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells8070763
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