Dynamics of circulating tumor DNA represented by the activating and resistant mutations in epidermal growth factor receptor tyrosine kinase inhibitor treatment

Circulating tumor DNA (ctDNA) is an emerging field of cancer research. For lung cancer, non‐invasive genotyping of EGFR is the foremost application. The activating mutations represent the ctDNA from all cancer cells, and the T790M‐resistant mutation represents that from resistant cells. We examined...

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Vydáno v:Cancer Sci
Hlavní autoři: Uchida, Junji, Imamura, Fumio, Kukita, Yoji, Oba, Shigeyuki, Kumagai, Toru, Nishino, Kazumi, Inoue, Takako, Kimura, Madoka, Kato, Kikuya
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2016
Témata:
Original Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4814247/
https://ncbi.nlm.nih.gov/pubmed/26678713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.12860
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