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Dynamics of circulating tumor DNA represented by the activating and resistant mutations in epidermal growth factor receptor tyrosine kinase inhibitor treatment

Circulating tumor DNA (ctDNA) is an emerging field of cancer research. For lung cancer, non‐invasive genotyping of EGFR is the foremost application. The activating mutations represent the ctDNA from all cancer cells, and the T790M‐resistant mutation represents that from resistant cells. We examined...

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Detalhes bibliográficos
Publicado no:Cancer Sci
Main Authors: Uchida, Junji, Imamura, Fumio, Kukita, Yoji, Oba, Shigeyuki, Kumagai, Toru, Nishino, Kazumi, Inoue, Takako, Kimura, Madoka, Kato, Kikuya
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4814247/
https://ncbi.nlm.nih.gov/pubmed/26678713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.12860
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