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Major SNP (Q141K) variant of Human ABC Transporter ABCG2 Undergoes Lysosomal and Proteasomal Degradations
PURPOSE: Single nucleotide polymorphisms (SNPs) of the ATP-binding cassette (ABC) transporter ABCG2 gene have been suggested to be a significant factor in patients’ responses to medication and/or the risk of diseases. We aimed to evaluate the impact of the major non-synonymous SNP Q141K on lysosomal...
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| Autori principali: | , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2008
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2628956/ https://ncbi.nlm.nih.gov/pubmed/18958403 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-008-9752-7 |
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