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Activating Mutations in PTPN11 and KRAS in Canine Histiocytic Sarcomas

While the genetic contributions to the predisposition of Bernese mountain dogs (BMDs) to histiocytic sarcoma (HS) remains unclear, some insights into key genetic drivers have been gained. Our group recently reported a mutation in the PTPN11 gene (E76K). We have now identified a second missense mutat...

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Detalhes bibliográficos
Publicado no:Genes (Basel)
Main Authors: Takada, Marilia, Smyth, Lauren A., Thaiwong, Tuddow, Richter, Marlee, Corner, Sarah M., Schall, Peter Z., Kiupel, Matti, Yuzbasiyan-Gurkan, Vilma
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6678586/
https://ncbi.nlm.nih.gov/pubmed/31277422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/genes10070505
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