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The Intrinsic GDP/GTP Exchange Activities of Cdc42 and Rac1 Are Critical Determinants for Their Specific Effects on Mobilization of the Actin Filament System

The Rho GTPases comprise a subfamily of the Ras superfamily of small GTPases. Their importance in regulation of cell morphology and cell migration is well characterized. According to the prevailing paradigm, Cdc42 regulates the formation of filopodia, Rac1 regulates the formation of lamellipodia, an...

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Detalhes bibliográficos
Publicado no:Cells
Autor principal: Aspenström, Pontus
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6678527/
https://ncbi.nlm.nih.gov/pubmed/31330900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells8070759
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