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Endocytosis of E-cadherin regulated by Rac and Cdc42 small G proteins through IQGAP1 and actin filaments

E-cadherin is a key cell–cell adhesion molecule at adherens junctions (AJs) and undergoes endocytosis when AJs are disrupted by the action of extracellular signals. To elucidate the mechanism of this endocytosis, we developed here a new cell-free assay system for this reaction using the AJ-enriched...

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Bibliografiske detaljer
Main Authors: Izumi, Genkichi, Sakisaka, Toshiaki, Baba, Takeshi, Tanaka, Shintaro, Morimoto, Koji, Takai, Yoshimi
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 2004
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2172308/
https://ncbi.nlm.nih.gov/pubmed/15263019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200401078
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