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Endocytosis of E-cadherin regulated by Rac and Cdc42 small G proteins through IQGAP1 and actin filaments

E-cadherin is a key cell–cell adhesion molecule at adherens junctions (AJs) and undergoes endocytosis when AJs are disrupted by the action of extracellular signals. To elucidate the mechanism of this endocytosis, we developed here a new cell-free assay system for this reaction using the AJ-enriched...

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Detalles Bibliográficos
Main Authors: Izumi, Genkichi, Sakisaka, Toshiaki, Baba, Takeshi, Tanaka, Shintaro, Morimoto, Koji, Takai, Yoshimi
Formato: Artigo
Idioma:Inglês
Publicado: The Rockefeller University Press 2004
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2172308/
https://ncbi.nlm.nih.gov/pubmed/15263019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200401078
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