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High Mobility Group Box 1 Mediates TMAO-Induced Endothelial Dysfunction

The intestinal microbe-derived metabolite trimethylamine N-oxide (TMAO) is implicated in the pathogenesis of cardiovascular diseases (CVDs). The molecular mechanisms of how TMAO induces atherosclerosis and CVDs’ progression are still unclear. In this regard, high-mobility group box protein 1 (HMGB1)...

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Pubblicato in:Int J Mol Sci
Autori principali: Singh, Gurinder Bir, Zhang, Yang, Boini, Krishna M., Koka, Saisudha
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6678463/
https://ncbi.nlm.nih.gov/pubmed/31336567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20143570
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