N-Methylparoxetine Blocked Autophagic Flux and Induced Apoptosis by Activating ROS-MAPK Pathway in Non-Small Cell Lung Cancer Cells

The main mechanistic function of most chemotherapeutic drugs is mediated by inducing mitochondria-dependent apoptosis. Tumor cells usually respond to upregulate autophagy to eliminate impaired mitochondria for survival. Hypothetically, inhibiting autophagy might promote mitochondria-dependent apopto...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Int J Mol Sci
Hlavní autoři: Wang, Kun, Chen, Bonan, Yin, Ting, Zhan, Yujuan, Lu, Yuhua, Zhang, Yilin, Chen, Jiawei, Wu, Weijie, Zhou, Shikun, Mao, Wenli, Tan, Yuhui, Du, Biaoyan, Liu, Xiaodong, HO, Hiuting Idy, Xiao, Jianyong
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2019
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6678301/
https://ncbi.nlm.nih.gov/pubmed/31336784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20143415
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky