Phc2 controls hematopoietic stem and progenitor cell mobilization from bone marrow by repressing Vcam1 expression

The timely mobilization of hematopoietic stem and progenitor cells (HSPCs) is essential for maintaining hematopoietic and tissue leukocyte homeostasis. Understanding how HSPCs migrate between bone marrow (BM) and peripheral tissues is of great significance in the clinical setting, where therapeutic...

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Vydáno v:Nat Commun
Hlavní autoři: Bae, Joonbeom, Choi, Sang-Pil, Isono, Kyoichi, Lee, Ji Yoon, Park, Si-Won, Choi, Chang-Yong, Han, Jihye, Kim, Sang-Hoon, Lee, Han-Hyoung, Park, Kyungmin, Jin, Hyun Yong, Lee, Suk Jun, Park, Chung-Gyu, Koseki, Haruhiko, Lee, Young Sik, Chun, Taehoon
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2019
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6677815/
https://ncbi.nlm.nih.gov/pubmed/31375680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-11386-4
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