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Class IIa HDACs regulate learning and memory through dynamic experience-dependent repression of transcription

The formation of new memories requires transcription. However, the mechanisms that limit signaling of relevant gene programs in space and time for precision of information coding remain poorly understood. We found that, during learning, the cellular patterns of expression of early response genes (ER...

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Vydáno v:Nat Commun
Hlavní autoři: Zhu, Yongchuan, Huang, Min, Bushong, Eric, Phan, Sebastien, Uytiepo, Marco, Beutter, Elizabeth, Boemer, Daniel, Tsui, Kristin, Ellisman, Mark, Maximov, Anton
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6677776/
https://ncbi.nlm.nih.gov/pubmed/31375688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-11409-0
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