Short-term CFTR inhibition reduces islet area in C57BL/6 mice

Cystic fibrosis-related diabetes (CFRD) worsens CF lung disease leading to early mortality. Loss of beta cell area, even without overt diabetes or pancreatitis is consistently observed. We investigated whether short-term CFTR inhibition was sufficient to impact islet morphology and function in other...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Khan, Dawood, Kelsey, Ryan, Maheshwari, Rashmi R., Stone, Virginia M., Hasib, Annie, Manderson Koivula, Fiona N., Watson, Aoife, Harkin, Stephen, Irwin, Nigel, Shaw, James A., McClenaghan, Neville H., Venglovecz, Viktória, Ébert, Attila, Flodström-Tullberg, Malin, White, Michael G., Kelly, Catriona
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2019
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6677757/
https://ncbi.nlm.nih.gov/pubmed/31375720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-47745-w
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker