The immune microenvironment in hormone receptor-positive breast cancer before and after preoperative chemotherapy

BACKGROUND: Hormone receptor-positive/HER2−negative (HR+/HER2−) breast cancer is associated with low levels of stromal tumor-infiltrating lymphocytes (sTIL) and PD-L1, and demonstrates poor responses to checkpoint inhibitor therapy. Evaluating the effect of standard chemotherapy on the immune microe...

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Detalhes bibliográficos
Publicado no:Clin Cancer Res
Main Authors: Waks, Adrienne G., Stover, Daniel G., Guerriero, Jennifer L., Dillon, Deborah, Barry, William T., Gjini, Evisa, Hartl, Christina, Lo, Wesley, Savoie, Jennifer, Brock, Jane, Wesolowski, Robert, Li, Zaibo, Damicis, Adrienne, Philips, Anne V., Wu, Yun, Yang, Fei, Sullivan, Amy, Danaher, Patrick, Brauer, Heather Ann, Osmani, Wafa, Lipschitz, Mikel, Hoadley, Katherine A., Goldberg, Michael, Perou, Charles M., Rodig, Scott, Winer, Eric P., Krop, Ian E., Mittendorf, Elizabeth A., Tolaney, Sara M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6677598/
https://ncbi.nlm.nih.gov/pubmed/31061067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-19-0173
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