Bevacizumab improves tumor infiltration of mature dendritic cells and effector T-cells in triple-negative breast cancer patients

A single dose of bevacizumab reduced the density of angiopoietin-2-positive vessels while improving the infiltration of CD4+ T and CD8+ T cells, and mature dendritic cells in patients with primary triple-negative breast cancer. Our findings provide a rationale for including bevacizumab during neoadj...

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Bibliographische Detailangaben
Veröffentlicht in:NPJ Precis Oncol
Hauptverfasser: Boucher, Yves, Kumar, Ashwin S., Posada, Jessica M., Gjini, Evisa, Pfaff, Kathleen, Lipschitz, Mikel, Lako, Ana, Duda, Dan G., Rodig, Scott J., Hodi, F. Stephen, Jain, Rakesh K.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2021
Schlagworte:
Brief Communication
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8242049/
https://ncbi.nlm.nih.gov/pubmed/34188163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41698-021-00197-w
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