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Synergistic Palladium/Enamine Catalysis for Asymmetric Hydrocarbon Functionalization of Unactivated Alkenes with Ketones

Synergistic palladium and enamine catalysis were explored to promote ketone addition to unactivated olefin. Secondary amine-based organocatalyst was identified as the optimal co-catalyst for the directed Pd-catalyzed alkene activation. Furthermore, asymmetric hydrocarbon functionalization of unactiv...

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Detalhes bibliográficos
Publicado no:Org Biomol Chem
Main Authors: Wei, Chiyu, Ye, Xiaohan, Xing, Qingyu, Hu, Yong, Xie, Yan, Shi, Xiaodong
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6677245/
https://ncbi.nlm.nih.gov/pubmed/31237304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c9ob01165j
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