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Catalytic Asymmetric Thiofunctionalization of Unactivated Alkenes

The catalytic asymmetric sulfenylation of double bonds has been achieved using a BINAM-based phosphoramide catalyst and electrophilic sulfur source. Simple alkenes as well as styrenes afforded sulfenylated tetrahydrofurans and tetrahydropyrans by closure with pendant hydroxyl or carboxyl groups. Int...

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Autors principals: Denmark, Scott E., Kornfilt, David J. P., Vogler, Thomas
Format: Artigo
Idioma:Inglês
Publicat: 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3187834/
https://ncbi.nlm.nih.gov/pubmed/21859086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja2064395
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