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Asymmetric Enzymatic Hydration of Unactivated, Aliphatic Alkenes
The direct enantioselective addition of water to unactivated alkenes could simplify the synthesis of chiral alcohols and solve a long‐standing challenge in catalysis. Here we report that an engineered fatty acid hydratase can catalyze the asymmetric hydration of various terminal and internal alkenes...
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| Publicado no: | Angew Chem Int Ed Engl |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6471033/ https://ncbi.nlm.nih.gov/pubmed/30256501 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201810005 |
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