Meox2 Haploinsufficiency Accelerates Axonal Degeneration in DBA/2J Glaucoma

PURPOSE: Glaucoma is a complex disease with major risk factors including advancing age and increased intraocular pressure (IOP). Dissecting these earliest events will likely identify new avenues for therapeutics. Previously, we performed transcriptional profiling in DBA/2J (D2) mice, a widely used m...

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Veröffentlicht in:Invest Ophthalmol Vis Sci
Hauptverfasser: Buchanan, Rebecca A., Foley, Kate E., Pepper, Keating W., Reagan, Alaina M., Keezer, Kelly J., Hewes, Amanda A., Diemler, Cory A., Preuss, Christoph, Soto, Ileana, John, Simon W. M., Howell, Gareth R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Association for Research in Vision and Ophthalmology 2019
Schlagworte:
Glaucoma
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6676925/
https://ncbi.nlm.nih.gov/pubmed/31369031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.18-26126
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