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An overactive neddylation pathway serves as a therapeutic target and MLN4924 enhances the anticancer activity of cisplatin in pancreatic cancer

The survival rate of patients with pancreatic cancer is between 3 and 5%. The neddylation pathway is overactive in multiple cancer types and is associated with poor prognosis. In recent years, the neddylation process has become a popular research target for the development of novel cancer therapies....

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Detalhes bibliográficos
Publicado no:Oncol Lett
Main Authors: Zeng, Yu, Iv, Yong-Shuang, Pan, Qi-Hua, Zhou, Yi-Guo, Li, He
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6676714/
https://ncbi.nlm.nih.gov/pubmed/31404297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2019.10596
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