Lamin-B1 is a senescence-associated biomarker in clear-cell renal cell carcinoma

Clear-cell renal cell carcinoma (ccRCC) is a von-Hippel-Lindau gene (VHL) associated tumor disease. In addition to activating the hypoxia inducible factor (HIF) dependent oxygen-sensing pathway, VHL loss also has an impact on a HIF-independent senescence program which functions as a tumorigenesis ba...

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Publicat a:Oncol Lett
Autors principals: Radspieler, Melissa Marie, Schindeldecker, Mario, Stenzel, Philipp, Försch, Sebastian, Tagscherer, Katrin E., Herpel, Esther, Hohenfellner, Markus, Hatiboglu, Gencay, Roth, Wilfried, Macher-Goeppinger, Stephan
Format: Artigo
Idioma:Inglês
Publicat: D.A. Spandidos 2019
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Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6676677/
https://ncbi.nlm.nih.gov/pubmed/31402955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2019.10593
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