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The effect of an alternative chromosome 17 probe on fluorescence in situ hybridization for the assessment of HER2 amplification in invasive breast cancer

Fluorescent in situ hybridization (FISH) is commonly used to determine the ratio of human epidermal growth factor receptor 2 (HER2) to centromere enumeration probe for chromosome 17 (CEP17), which further determines HER2 gene status in breast cancer. However, due to copy number alteration in CEP17,...

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Bibliographic Details
Published in:Exp Ther Med
Main Authors: Xu, Zhigao, Xu, Peipei, Fan, Wei, Huang, Ben, Cheng, Qingyuan, Zhang, Zheng, Wang, Ping, Yu, Mingxia
Format: Artigo
Language:Inglês
Published: D.A. Spandidos 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6676089/
https://ncbi.nlm.nih.gov/pubmed/31410164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/etm.2019.7756
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