Clinicopathologic Features of Breast Cancer Reclassified as HER2-Amplified by Fluorescence In Situ Hybridization with Alternative Chromosome 17 Probes

OBJECTIVE: Dual probe fluorescence in situ hybridization (FISH) assays for determination of human epidermal growth factor receptor 2 (HER2) gene amplification in breast cancer provide a ratio of HER2 to chromosome 17. The ratio may be skewed by copy number alterations (CNA) in the control locus for...

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Pubblicato in:Ann Diagn Pathol
Autori principali: Blanton, Kristen C, Deal, Allison M., Kaiser-Rogers, Kathleen A., Anders, Carey K., O’Connor, Siobhan M., Hertel, Johann D., Calhoun, Benjamin C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2020
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7907993/
https://ncbi.nlm.nih.gov/pubmed/32805517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.anndiagpath.2020.151576
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