Gold-Facilitated in Situ Hybridization : A Bright-Field Autometallographic Alternative to Fluorescence in Situ Hybridization for Detection of HER-2/neu Gene Amplification

Fluorescence in situ hybridization (FISH) represents an excellent method for profiling gene amplification in situ, but correlation with tissue morphology is difficult because of dark-field visualization. Validation of a bright-field assay for assessment of HER-2/neu gene amplification was investigat...

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Detalhes bibliográficos
Main Authors: Tubbs, Raymond, Pettay, James, Skacel, Marek, Powell, Richard, Stoler, Mark, Roche, Patrick, Hainfeld, James
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2002
Assuntos:
Technical Advance
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1850888/
https://ncbi.nlm.nih.gov/pubmed/12000711
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