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Metachromatic leukodystrophy: Characterization of two (p.Leu433Val, p.Gly449Arg) arylsulfatase A mutations

Metachromatic leukodystrophy disorder (MLD) is an autosomal recessive lysosomal storage disease. The disease is primarily caused by a deficiency in the enzyme arylsulfatase A (ASA), which is encoded by the ARSA gene. A total of 254 mutations have been reported in different populations. The present s...

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Detalhes bibliográficos
Publicado no:Exp Ther Med
Principais autores: Wang, Yangyang, Chen, Xiang, Liu, Chan, Wu, Shamin, Xie, Qingfeng, Hu, Quan, Chen, Shan, Liu, Yiwei
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6676083/
https://ncbi.nlm.nih.gov/pubmed/31410132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/etm.2019.7760
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