Spatiotemporal Analysis of Hepatitis B Virus X Protein in Primary Human Hepatocytes

The structural maintenance of chromosomes 5/6 complex (Smc5/6) is a host restriction factor that suppresses hepatitis B virus (HBV) transcription. HBV counters this restriction by expressing the X protein (HBx), which redirects the host DNA damage-binding protein 1 (DDB1) E3 ubiquitin ligase to targ...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Kornyeyev, Dmytro, Ramakrishnan, Dhivya, Voitenleitner, Christian, Livingston, Christine M., Xing, Weimei, Hung, Magdeleine, Kwon, Hyock Joo, Fletcher, Simon P., Beran, Rudolf K.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2019
Assuntos:
Virus-Cell Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6675897/
https://ncbi.nlm.nih.gov/pubmed/31167911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00248-19
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