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Aberrant X chromosome skewing and acquired clonal hematopoiesis in adult-onset common variable immunodeficiency

Advances in genomic medicine have elucidated an increasing number of genetic etiologies for patients with common variable immunodeficiency (CVID). However, there is heterogeneity in clinical and immunophenotypic presentations and a limited understanding of the underlying pathophysiology of many case...

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Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: Wong, Gabriel K., Barmettler, Sara, Heather, James M., Millar, David, Penny, Sarah A., Huissoon, Aarnoud, Richter, Alex, Cobbold, Mark
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6675553/
https://ncbi.nlm.nih.gov/pubmed/31341110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.127614
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