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Accelerated Loss of TCR Repertoire Diversity in Common Variable Immunodeficiency

Although common variable immunodeficiency (CVID) has long been considered as a group of primary Ab deficiencies, growing experimental data now suggest a global disruption of the entire adaptive immune response in a segment of patients. Oligoclonality of the TCR repertoire was previously demonstrated...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Wong, Gabriel K., Millar, David, Penny, Sarah, Heather, James M., Mistry, Punam, Buettner, Nico, Bryon, Jane, Huissoon, Aarnoud P., Cobbold, Mark
Formato: Artigo
Idioma:Inglês
Publicado em: AAI 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4991247/
https://ncbi.nlm.nih.gov/pubmed/27481850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1600526
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