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T-cell abnormalities in common variable immunodeficiency: the hidden defect

This review discusses how the T-cell compartment in common variable immunodeficiency is marked by the premature arrest in thymic output, leading to T-cell exhaustion and immune dysregulation. Although B cells have been the main focus of the disorder, ample experimental data suggest that T-cell abnor...

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Podrobná bibliografie
Vydáno v:J Clin Pathol
Hlavní autoři: Wong, Gabriel K, Huissoon, Aarnoud P
Médium: Artigo
Jazyk:Inglês
Vydáno: BMJ Publishing Group 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4975840/
https://ncbi.nlm.nih.gov/pubmed/27153873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jclinpath-2015-203351
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