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T-cell abnormalities in common variable immunodeficiency: the hidden defect
This review discusses how the T-cell compartment in common variable immunodeficiency is marked by the premature arrest in thymic output, leading to T-cell exhaustion and immune dysregulation. Although B cells have been the main focus of the disorder, ample experimental data suggest that T-cell abnor...
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| Publicado no: | J Clin Pathol |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BMJ Publishing Group
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4975840/ https://ncbi.nlm.nih.gov/pubmed/27153873 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jclinpath-2015-203351 |
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