Strategies for B-Cell Receptor Repertoire Analysis in Primary Immunodeficiencies: From Severe Combined Immunodeficiency to Common Variable Immunodeficiency

The antigen receptor repertoires of B- and T-cells form the basis of the adaptive immune response. The repertoires should be sufficiently diverse to recognize all possible pathogens. However, careful selection is needed to prevent responses to self or harmless antigens. Limited antigen receptor repe...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: IJspeert, Hanna, Wentink, Marjolein, van Zessen, David, Driessen, Gertjan J., Dalm, Virgil A. S. H., van Hagen, Martin P., Pico-Knijnenburg, Ingrid, Simons, Erik J., van Dongen, Jacques J. M., Stubbs, Andrew P., van der Burg, Mirjam
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2015
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4389565/
https://ncbi.nlm.nih.gov/pubmed/25904919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2015.00157
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