Metabolism of 3-Nitrotyrosine Induces Apoptotic Death in Dopaminergic Cells

Intrastriatal injection of 3-nitrotyrosine, which is a biomarker for nitrating oxidants, provokes dopaminergic neuronal death in rats by unknown mechanisms. Herein, we show that extracellular 3-nitrotyrosine is transported via the l-aromatic amino acid transporter in nondopaminergic NT2 cells, where...

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Publicat a:J Neurosci
Autors principals: Blanchard-Fillion, Béatrice, Prou, Delphine, Polydoro, Manuela, Spielberg, David, Tsika, Elpida, Wang, Zeneng, Hazen, Stanley L., Koval, Michael, Przedborski, Serge, Ischiropoulos, Harry
Format: Artigo
Idioma:Inglês
Publicat: Society for Neuroscience 2006
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Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6675196/
https://ncbi.nlm.nih.gov/pubmed/16763020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1038-06.2006
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