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Oxidative modifications, mitochondrial dysfunction, and impaired protein degradation in Parkinson's disease: how neurons are lost in the Bermuda triangle

While numerous hypotheses have been proposed to explain the molecular mechanisms underlying the pathogenesis of neurodegenerative diseases, the theory of oxidative stress has received considerable support. Although many correlations have been established and encouraging evidence has been obtained, c...

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Bibliographic Details
Main Authors: Malkus, Kristen A, Tsika, Elpida, Ischiropoulos, Harry
Format: Artigo
Language:Inglês
Published: BioMed Central 2009
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2701947/
https://ncbi.nlm.nih.gov/pubmed/19500376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1750-1326-4-24
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