TP53 codon 72 polymorphism is associated with FGFR3 and RAS mutation in non-muscle-invasive bladder cancer

OBJECTIVE: TP53, a well-known tumor-suppressor gene in bladder carcinogenesis, has a functional single-nucleotide polymorphism on codon 72. The aim of this study was to elucidate the association between TP53 codon 72 polymorphism and somatic mutations in bladder cancer. MATERIAL AND METHODS: Germlin...

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Udgivet i:PLoS One
Main Authors: Kawahara, Takashi, Kojima, Takahiro, Kandori, Shuya, Kurobe, Masahiro, Yoshino, Takayuki, Kimura, Tomokazu, Nagumo, Yoshiyuki, Ishituka, Ryutaro, Mitsuzuka, Koji, Narita, Shintaro, Kobayashi, Takashi, Matsui, Yoshiyuki, Ogawa, Osamu, Sugimoto, Mikio, Miyazaki, Jun, Nishiyama, Hiroyuki
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2019
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6675066/
https://ncbi.nlm.nih.gov/pubmed/31369573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0220173
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