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Browning of White Adipose Tissue with Roscovitine Induces a Distinct Population of UCP1(+) Adipocytes

Brown-like adipocytes exist in several adipose depots including white (WAT) as well as brown (BAT). Activation of these UCP1(+) cells is a potential therapeutic strategy to combat obesity. Studies have shown that posttranslational modifications of PPARγ regulate select adipocyte programs. Deacetylat...

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Vydáno v:Cell Metab
Hlavní autoři: Wang, Hong, Liu, Libin, Lin, Jean Z., Aprahamian, Tamar R., Farmer, Stephen R.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6674884/
https://ncbi.nlm.nih.gov/pubmed/27974179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2016.10.005
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