p25/Cyclin-Dependent Kinase 5 Induces Production and Intraneuronal Accumulation of Amyloid β In Vivo

Aberrant processing of the amyloid precursor protein (APP) and the subsequent accumulation of amyloid β (Aβ) peptide has been widely established as a central event in Alzheimer's disease (AD) pathogenesis. The sequential cleavage steps required for the generation of Aβ are well outlined; howeve...

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Bibliografiske detaljer
Udgivet i:J Neurosci
Main Authors: Cruz, Jonathan C., Kim, Dohoon, Moy, Lily Y., Dobbin, Matthew M., Sun, Xiaoyan, Bronson, Roderick T., Tsai, Li-Huei
Format: Artigo
Sprog:Inglês
Udgivet: Society for Neuroscience 2006
Fag:
Brief Communications
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6674706/
https://ncbi.nlm.nih.gov/pubmed/17035538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3133-06.2006
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