p35 and p39 Are Essential for Cyclin-Dependent Kinase 5 Function during Neurodevelopment

Cyclin-dependent kinase 5 (Cdk5) plays a pivotal role in brain development and neuronal migration. Cdk5 is abundant in postmitotic, terminally differentiated neurons. The ability of Cdk5 to phosphorylate substrates is dependent on activation by its neuronal-specific activators p35 and p39. There exi...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Ko, Jane, Humbert, Sandrine, Bronson, Roderick T., Takahashi, Satoru, Kulkarni, Ashok B., Li, En, Tsai, Li-Huei
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2001
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ARTICLE
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6763073/
https://ncbi.nlm.nih.gov/pubmed/11517264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.21-17-06758.2001
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