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The Activators of Cyclin-Dependent Kinase 5 p35 and p39 Are Essential for Oligodendrocyte Maturation, Process Formation, and Myelination

The regulation of oligodendrocyte development and myelin formation in the CNS is poorly defined. Multiple signals influence the rate and extent of CNS myelination, including the noncanonical cyclin-dependent kinase 5 (Cdk5) whose functions are regulated by its activators p35 and p39. Here we show th...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Luo, Fucheng, Zhang, Jessie, Burke, Kathryn, Miller, Robert H., Yang, Yan
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4783501/
https://ncbi.nlm.nih.gov/pubmed/26961956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2250-15.2016
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