Novel Agonist Monoclonal Antibodies Activate TrkB Receptors and Demonstrate Potent Neurotrophic Activities

Tyrosine kinase receptor B (TrkB) mediates neurotrophic effects of brain-derived neurotrophic factor (BDNF) to increase neuronal survival, differentiation, synaptic plasticity, and neurogenesis. The therapeutic potential of TrkB activation using BDNF has been demonstrated well in several preclinical...

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Bibliographic Details
Published in:J Neurosci
Main Authors: Qian, Ming D., Zhang, Jie, Tan, Xiang-Yang, Wood, Andrew, Gill, Davinder, Cho, Seongeun
Format: Artigo
Language:Inglês
Published: Society for Neuroscience 2006
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6674613/
https://ncbi.nlm.nih.gov/pubmed/16971523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1118-06.2006
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