Transgenic Rescue of ataxia Mice with Neuronal-Specific Expression of Ubiquitin-Specific Protease 14

The ataxia mutation (ax(J)) is a recessive neurological mutation that results in reduced growth, ataxia, and hindlimb muscle wasting in mice. The ax(J) gene encodes ubiquitin-specific protease 14 (Usp14), a deubiquitinating enzyme (DUB) that associates with the proteasome via its ubiquitin-like (Ubl...

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Vydáno v:J Neurosci
Hlavní autoři: Crimmins, Stephen, Jin, Youngam, Wheeler, Crystal, Huffman, Alexis K., Chapman, Carlene, Dobrunz, Lynn E., Levey, Alan, Roth, Kevin A., Wilson, Julie A., Wilson, Scott M.
Médium: Artigo
Jazyk:Inglês
Vydáno: Society for Neuroscience 2006
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6674543/
https://ncbi.nlm.nih.gov/pubmed/17079671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3600-06.2006
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