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Transgenic Rescue of ataxia Mice with Neuronal-Specific Expression of Ubiquitin-Specific Protease 14
The ataxia mutation (ax(J)) is a recessive neurological mutation that results in reduced growth, ataxia, and hindlimb muscle wasting in mice. The ax(J) gene encodes ubiquitin-specific protease 14 (Usp14), a deubiquitinating enzyme (DUB) that associates with the proteasome via its ubiquitin-like (Ubl...
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| izdano v: | J Neurosci |
|---|---|
| Main Authors: | , , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Society for Neuroscience
2006
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6674543/ https://ncbi.nlm.nih.gov/pubmed/17079671 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3600-06.2006 |
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