Deletion of the GABA(A) Receptor α1 Subunit Increases Tonic GABA(A) Receptor Current: A Role for GABA Uptake Transporters

The loss of more than half the number of GABA(A) receptors yet lack of pronounced phenotype in mice lacking the gene for the GABA(A) α1 subunit is somewhat paradoxical. We explored the role of tonic GABA(A) receptor-mediated current as a target of compensatory regulation in the α1 knock-out (−/−) mi...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:J Neurosci
Hauptverfasser: Ortinski, Pavel I., Turner, Jill R., Barberis, Andrea, Motamedi, Gholam, Yasuda, Robert P., Wolfe, Barry B., Kellar, Kenneth J., Vicini, Stefano
Format: Artigo
Sprache:Inglês
Veröffentlicht: Society for Neuroscience 2006
Schlagworte:
Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6674491/
https://ncbi.nlm.nih.gov/pubmed/16957088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2610-06.2006
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge