RTP801 Is Elevated in Parkinson Brain Substantia Nigral Neurons and Mediates Death in Cellular Models of Parkinson's Disease by a Mechanism Involving Mammalian Target of Rapamycin Inactivation

The molecules underlying neuron loss in Parkinson's disease (PD) are essentially unknown, and current therapies focus on diminishing symptoms rather than preventing neuron death. We identified RTP801 as a gene whose transcripts were highly induced in a cellular model of PD in which death of neu...

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Detaylı Bibliyografya
Yayımlandı:J Neurosci
Asıl Yazarlar: Malagelada, Cristina, Ryu, Elizabeth J., Biswas, Subhas C., Jackson-Lewis, Vernice, Greene, Lloyd A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Society for Neuroscience 2006
Konular:
Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6674487/
https://ncbi.nlm.nih.gov/pubmed/17005863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3292-06.2006
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